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- Generic platinum chemotherapy shortages did not increase deathsAn analysis of national data found that short-term mortality was not impacted for patients with advanced cancers during the shortage of the generic platinum chemotherapy drugs cisplatin and carboplatin that began in early 2023.
- A low omega-6, omega-3 rich diet and fish oil may slow prostate cancer growthA new study offers new evidence that dietary changes may help reduce cancer cell growth in patients undergoing active surveillance, a treatment approach that involves regular monitoring of the cancer without immediate intervention. Men on active surveillance who followed a low omega-6, high omega-3 diet with fish oil supplements had significantly lower levels of cancer […]
- Key regulator that induces cancer-killing capacity in T cells under hypoxia is identifiedImmune checkpoint blockades, or ICBs, have revolutionized treatment for various advanced cancers. However, their effectiveness has plateaued due to therapeutic resistance that renders tumor-infiltrating lymphocytes, or TILs, ineffective. Thus, finding ways to disarm that resistance and rejuvenate anti-cancer TILs so they can kill tumor cells is an important goal for cancer clinicians.
- AI tool analyzes placentas at birth for faster detection of neonatal, maternal problemsA newly developed tool that harnesses computer vision and artificial intelligence (AI) may help clinicians from around the globe rapidly evaluate placentas at birth, potentially improving neonatal and maternal care. Early identification of placental infection could help mothers and babies receive antibiotics. The tool would be helpful for doctors in low-resource areas with no pathology […]
- Unlocking the potential to better target cancer with immunotherapyCancer immunotherapy has revolutionized treatment for patients, whereby the body's own immune system is harnessed to destroy cancer cells. Typically, several molecules restrain the ability of T cells to target cancer cells and developing approaches to limit this restraining effect can lead to improved effectiveness of cancer immunotherapy. Research has now determined the structure of […]
- A new twist: The molecular machines that loop our chromosomes also twist DNAScientists have discovered a new property of the molecular motors that shape our chromosomes. While six years ago they found that these so-called SMC motor proteins make long loops in our DNA, they now discovered that these motors also put significant twists into the loops that they form. These findings help us better understand the […]
- Combined screening can detect liver damage in diabetes patientsNew research highlights the possibility of screening people with type 2 diabetes for liver damage at the same time as they undergo screening for eye disease.
- Faster, safer complex head and neck reconstruction with preserved blood supply tissueResearchers have developed a new technique for head and neck reconstruction using a pedicled latissimus dorsi flap. This approach offers a safer, faster alternative for high-risk patients, achieving a 100% success rate in 22 cases with complex defects.
- From Yemen to Mayotte, the spread of a highly drug-resistant cholera strainScientists have revealed the spread of a highly drug-resistant cholera strain.
- Activating the hidden pharmaceutical potential of bacteriaMicroorganisms produce a wide variety of natural products that can be used as active ingredients to treat diseases such as infections or cancer. The blueprints for these molecules can be found in the microbes' genes, but often remain inactive under laboratory conditions. A team of researchers has now developed a groundbreaking genetic method that leverages […]
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